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BMCBI
2006
121views more  BMCBI 2006»
13 years 7 months ago
Splice site identification using probabilistic parameters and SVM classification
Background: Recent advances and automation in DNA sequencing technology has created a vast amount of DNA sequence data. This increasing growth of sequence data demands better and ...
A. K. M. A. Baten, Bill C. H. Chang, Saman K. Halg...
BMCBI
2008
128views more  BMCBI 2008»
13 years 7 months ago
Nonparametric relevance-shifted multiple testing procedures for the analysis of high-dimensional multivariate data with small sa
Background: In many research areas it is necessary to find differences between treatment groups with several variables. For example, studies of microarray data seek to find a sign...
Cornelia Frömke, Ludwig A. Hothorn, Siegfried...
BMCBI
2010
143views more  BMCBI 2010»
13 years 7 months ago
Shape based kinetic outlier detection in real-time PCR
Background: Real-time PCR has recently become the technique of choice for absolute and relative nucleic acid quantification. The gold standard quantification method in real-time P...
Davide Sisti, Michele Guescini, Marco B. L. Rocchi...
BMCBI
2007
194views more  BMCBI 2007»
13 years 7 months ago
A meta-data based method for DNA microarray imputation
Background: DNA microarray experiments are conducted in logical sets, such as time course profiling after a treatment is applied to the samples, or comparisons of the samples unde...
Rebecka Jörnsten, Ming Ouyang, Hui-Yu Wang
BMCBI
2008
108views more  BMCBI 2008»
13 years 7 months ago
New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic backgroun
Background: Few genetic factors predisposing to the sporadic form of amyotrophic lateral sclerosis (ALS) have been identified, but the pathology itself seems to be a true multifac...
Silvana Penco, Massimo Buscema, Maria Cristina Pat...