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BMCBI
2006
114views more  BMCBI 2006»
13 years 9 months ago
Mining frequent patterns for AMP-activated protein kinase regulation on skeletal muscle
Background: AMP-activated protein kinase (AMPK) has emerged as a significant signaling intermediary that regulates metabolisms in response to energy demand and supply. An investig...
Qingfeng Chen, Yi-Ping Phoebe Chen
BMCBI
2006
92views more  BMCBI 2006»
13 years 9 months ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...
BMCBI
2006
137views more  BMCBI 2006»
13 years 9 months ago
Curation of complex, context-dependent immunological data
Background: The Immune Epitope Database and Analysis Resource (IEDB) is dedicated to capturing, housing and analyzing complex immune epitope related data http:// www.immuneepitope...
Randi Vita, Kerrie Vaughan, Laura Zarebski, Nima S...
BMCBI
2006
149views more  BMCBI 2006»
13 years 9 months ago
Identification of biomarkers from mass spectrometry data using a "common" peak approach
Background: Proteomic data obtained from mass spectrometry have attracted great interest for the detection of early-stage cancer. However, as mass spectrometry data are high-dimen...
Tadayoshi Fushiki, Hironori Fujisawa, Shinto Eguch...
BMCBI
2006
132views more  BMCBI 2006»
13 years 9 months ago
Genome-wide DNA polymorphism analyses using VariScan
Background: DNA sequence polymorphisms analysis can provide valuable information on the evolutionary forces shaping nucleotide variation, and provides an insight into the function...
Stephan Hutter, Albert J. Vilella, Julio Rozas