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» Recent developments in the MAFFT multiple sequence alignment...
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BMCBI
2004
177views more  BMCBI 2004»
13 years 7 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
BMCBI
2007
126views more  BMCBI 2007»
13 years 7 months ago
Multiple non-collinear TF-map alignments of promoter regions
Background: The analysis of the promoter sequence of genes with similar expression patterns is a basic tool to annotate common regulatory elements. Multiple sequence alignments ar...
Enrique Blanco, Roderic Guigó, Xavier Messe...
BMCBI
2004
96views more  BMCBI 2004»
13 years 7 months ago
Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides
Background: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequen...
Olga V. Matveeva, Brian T. Foley, Vladimir A. Nemt...
BMCBI
2011
12 years 11 months ago
A user-friendly web portal for T-Coffee on supercomputers
Background: Parallel T-Coffee (PTC) was the first parallel implementation of the T-Coffee multiple sequence alignment tool. It is based on MPI and RMA mechanisms. Its purpose is t...
Josep Rius Torrento, Fernando Cores, Francesc Sols...
CISIS
2010
IEEE
14 years 2 months ago
Scalability Analysis of Progressive Alignment on a Multicore
—Sequence alignment is a fundamental instrument in Bioinformatics. In recent years, numerous proposals have been addressing the problem of accelerating this class of applications...
Sebastian Isaza, Friman Sánchez, Georgi Gay...