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BMCBI
2010
86views more  BMCBI 2010»
15 years 4 months ago
Protein binding hot spots and the residue-residue pairing preference: a water exclusion perspective
Background: A protein binding hot spot is a small cluster of residues tightly packed at the center of the interface between two interacting proteins. Though a hot spot constitutes...
Qian Liu, Jinyan Li
BMCBI
2010
106views more  BMCBI 2010»
15 years 4 months ago
Multiple structure alignment and consensus identification for proteins
Background: An algorithm is presented to compute a multiple structure alignment for a set of proteins and to generate a consensus (pseudo) protein which captures common substructu...
Ivaylo Ilinkin, Jieping Ye, Ravi Janardan
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BMCBI
2010
94views more  BMCBI 2010»
15 years 4 months ago
A high-throughput pipeline for the design of real-time PCR signatures
Background: Pathogen diagnostic assays based on polymerase chain reaction (PCR) technology provide high sensitivity and specificity. However, the design of these diagnostic assays...
Ravi Vijaya Satya, Kamal Kumar, Nela Zavaljevski, ...
BMCBI
2007
136views more  BMCBI 2007»
15 years 4 months ago
Genomorama: genome visualization and analysis
Background: The ability to visualize genomic features and design experimental assays that can target specific regions of a genome is essential for modern biology. To assist in the...
Jason D. Gans, Murray Wolinsky
BMCBI
2007
86views more  BMCBI 2007»
15 years 4 months ago
Detecting microsatellites within genomes: significant variation among algorithms
Background: Microsatellites are short, tandemly-repeated DNA sequences which are widely distributed among genomes. Their structure, role and evolution can be analyzed based on exh...
Sébastien Leclercq, Eric Rivals, Philippe J...
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