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ISMB
2000
13 years 8 months ago
Pattern Recognition of Genomic Features with Microarrays: Site Typing of Mycobacterium Tuberculosis Strains
Mycobacterium tuberculosis (M. tb.) strains differ in the number and locations of a transposon-like insertion sequence known as IS6110. Accurate detection of this sequence can be ...
Soumya Raychaudhuri, Joshua M. Stuart, Xuemin Liu,...
BMCBI
2007
114views more  BMCBI 2007»
13 years 7 months ago
Large scale statistical inference of signaling pathways from RNAi and microarray data
Background: The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray tec...
Holger Fröhlich, Mark Fellmann, Holger Sü...
BIOSYSTEMS
2007
115views more  BIOSYSTEMS 2007»
13 years 7 months ago
Evolving fuzzy rules to model gene expression
This paper develops an algorithm that extracts explanatory rules from microarray data, which we treat as time series, using genetic programming (GP) and fuzzy logic. Reverse polis...
Ricardo Linden, Amit Bhaya
BMCBI
2007
168views more  BMCBI 2007»
13 years 7 months ago
Bayesian model-based inference of transcription factor activity
Background: In many approaches to the inference and modeling of regulatory interactions using microarray data, the expression of the gene coding for the transcription factor is co...
Simon Rogers, Raya Khanin, Mark Girolami
BMCBI
2006
157views more  BMCBI 2006»
13 years 7 months ago
Determination of the minimum number of microarray experiments for discovery of gene expression patterns
Background: One type of DNA microarray experiment is discovery of gene expression patterns for a cell line undergoing a biological process over a series of time points. Two import...
Fang-Xiang Wu, W. J. Zhang, Anthony J. Kusalik