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» Reconstruction of biological networks based on life science ...
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CIKM
2003
Springer
14 years 23 days ago
HyperThesis: the gRNA spell on the curse of bioinformatics applications integration
In this paper, we describe a graphical workflow management system called HyperThesis to address the challenges of integrating bioinformatics applications. HyperThesis is an integ...
Sourav S. Bhowmick, Vivek Vedagiri, Amey V. Laud
BMCBI
2007
200views more  BMCBI 2007»
13 years 7 months ago
BNDB - The Biochemical Network Database
Background: Technological advances in high-throughput techniques and efficient data acquisition methods have resulted in a massive amount of life science data. The data is stored ...
Jan Küntzer, Christina Backes, Torsten Blum, ...
BMCBI
2006
153views more  BMCBI 2006»
13 years 7 months ago
Discovery of time-delayed gene regulatory networks based on temporal gene expression profiling
Background: It is one of the ultimate goals for modern biological research to fully elucidate the intricate interplays and the regulations of the molecular determinants that prope...
Xia Li, Shaoqi Rao, Wei Jiang, Chuanxing Li, Yun X...
GECCO
2005
Springer
127views Optimization» more  GECCO 2005»
14 years 1 months ago
Identifying valid solutions for the inference of regulatory networks
In this paper, we address the problem of finding gene regulatory networks from experimental DNA microarray data. The problem often is multi-modal and therefore appropriate optimi...
Christian Spieth, Felix Streichert, Nora Speer, An...
BMCBI
2005
159views more  BMCBI 2005»
13 years 7 months ago
Columba: an integrated database of proteins, structures, and annotations
Background: Structural and functional research often requires the computation of sets of protein structures based on certain properties of the proteins, such as sequence features,...
Silke Trißl, Kristian Rother, Heiko Mül...