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BMCBI
2007
116views more  BMCBI 2007»
13 years 8 months ago
MED: a new non-supervised gene prediction algorithm for bacterial and archaeal genomes
Background: Despite a remarkable success in the computational prediction of genes in Bacteria and Archaea, a lack of comprehensive understanding of prokaryotic gene structures pre...
Huaiqiu Zhu, Gang-Qing Hu, Yi-Fan Yang, Jin Wang, ...
BMCBI
2010
86views more  BMCBI 2010»
13 years 8 months ago
Mining protein loops using a structural alphabet and statistical exceptionality
Background: Protein loops encompass 50% of protein residues in available three-dimensional structures. These regions are often involved in protein functions, e.g. binding site, ca...
Leslie Regad, Juliette Martin, Grégory Nuel...
BMCBI
2007
139views more  BMCBI 2007»
13 years 8 months ago
XSTREAM: A practical algorithm for identification and architecture modeling of tandem repeats in protein sequences
Background: Biological sequence repeats arranged in tandem patterns are widespread in DNA and proteins. While many software tools have been designed to detect DNA tandem repeats (...
Aaron M. Newman, James B. Cooper
BMCBI
2011
13 years 3 months ago
Errors in CGAP xProfiler and cDNA DGED: the importance of library parsing and gene selection algorithms
Background: The Cancer Genome Anatomy Project (CGAP) xProfiler and cDNA Digital Gene Expression Displayer (DGED) have been made available to the scientific community over a decade...
Andrew T. Milnthorpe, Mikhail Soloviev
BMCBI
2006
124views more  BMCBI 2006»
13 years 8 months ago
Detection of divergent genes in microbial aCGH experiments
Background: Array-based comparative genome hybridization (aCGH) is a tool for rapid comparison of genomes from different bacterial strains. The purpose of such analysis is to dete...
Lars Snipen, Dirk Repsilber, Ludvig Nyquist, &Arin...