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SIGMOD
2011
ACM
150views Database» more  SIGMOD 2011»
13 years 14 days ago
WHAM: a high-throughput sequence alignment method
Over the last decade the cost of producing genomic sequences has dropped dramatically due to the current so called “next-gen” sequencing methods. However, these next-gen seque...
Yinan Li, Allison Terrell, Jignesh M. Patel
BMCBI
2008
149views more  BMCBI 2008»
13 years 9 months ago
Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment s
Background: Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic d...
Olivier Bastien, Eric Maréchal
CACM
2005
74views more  CACM 2005»
13 years 9 months ago
Separate handles from names on the internet
Networked communications inherently depend on the ability of the sender of a message to indicate through some token how the message should be delivered to a particular recipient. ...
Michael J. O'Donnell
BMCBI
2008
97views more  BMCBI 2008»
13 years 9 months ago
Large-scale directional relationship extraction and resolution
Background: Relationships between entities such as genes, chemicals, metabolites, phenotypes and diseases in MEDLINE are often directional. That is, one may affect the other in a ...
Cory B. Giles, Jonathan D. Wren
PSSS
2003
13 years 11 months ago
Representing Contextualized Data using Semantic Web Tools
: RDF-based tools promise to provide a base for reasoning about metadata and about situated data—data describing entities situated in time and space—that is superior to alterna...
Robert M. MacGregor, In-Young Ko