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» Reflections on a Geometry of Processes
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BMCBI
2006
117views more  BMCBI 2006»
13 years 9 months ago
SigFlux: A novel network feature to evaluate the importance of proteins in signal transduction networks
Background: Measuring each protein's importance in signaling networks helps to identify the crucial proteins in a cellular process, find the fragile portion of the biology sy...
Wei Liu, Dong Li, Jiyang Zhang, Yunping Zhu, Fuchu...
BMCBI
2007
96views more  BMCBI 2007»
13 years 9 months ago
Features generated for computational splice-site prediction correspond to functional elements
Background: Accurate selection of splice sites during the splicing of precursors to messenger RNA requires both relatively well-characterized signals at the splice sites and auxil...
Rezarta Islamaj Dogan, Lise Getoor, W. John Wilbur...
BMCBI
2007
168views more  BMCBI 2007»
13 years 9 months ago
Bayesian model-based inference of transcription factor activity
Background: In many approaches to the inference and modeling of regulatory interactions using microarray data, the expression of the gene coding for the transcription factor is co...
Simon Rogers, Raya Khanin, Mark Girolami
JCNS
2008
64views more  JCNS 2008»
13 years 9 months ago
Spike-frequency adaptation generates intensity invariance in a primary auditory interneuron
Adaptation of the spike-frequency response to constant stimulation, as observed on various timescales in many neurons, reflects high-pass filter properties of a neuron's tran...
Jan Benda, Matthias Hennig
JMLR
2008
129views more  JMLR 2008»
13 years 9 months ago
Finite-Time Bounds for Fitted Value Iteration
In this paper we develop a theoretical analysis of the performance of sampling-based fitted value iteration (FVI) to solve infinite state-space, discounted-reward Markovian decisi...
Rémi Munos, Csaba Szepesvári