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» Regression analysis of multiple protein structures
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BMCBI
2008
165views more  BMCBI 2008»
13 years 7 months ago
Peak intensity prediction in MALDI-TOF mass spectrometry: A machine learning study to support quantitative proteomics
Background: Mass spectrometry is a key technique in proteomics and can be used to analyze complex samples quickly. One key problem with the mass spectrometric analysis of peptides...
Wiebke Timm, Alexandra Scherbart, Sebastian Bö...
BMCBI
2007
109views more  BMCBI 2007»
13 years 7 months ago
A domain-based approach to predict protein-protein interactions
Background: Knowing which proteins exist in a certain organism or cell type and how these proteins interact with each other are necessary for the understanding of biological proce...
Mudita Singhal, Haluk Resat
BMCBI
2006
130views more  BMCBI 2006»
13 years 7 months ago
4SALE - A tool for synchronous RNA sequence and secondary structure alignment and editing
Background: In sequence analysis the multiple alignment builds the fundament of all proceeding analyses. Errors in an alignment could strongly influence all succeeding analyses an...
Philipp N. Seibel, Tobias Müller, Thomas Dand...
BMCBI
2008
138views more  BMCBI 2008»
13 years 7 months ago
Application of nonnegative matrix factorization to improve profile-profile alignment features for fold recognition and remote ho
Background: Nonnegative matrix factorization (NMF) is a feature extraction method that has the property of intuitive part-based representation of the original features. This uniqu...
Inkyung Jung, Jaehyung Lee, Soo-Young Lee, Dongsup...
BMCBI
2007
132views more  BMCBI 2007»
13 years 7 months ago
On the analysis of glycomics mass spectrometry data via the regularized area under the ROC curve
Background: Novel molecular and statistical methods are in rising demand for disease diagnosis and prognosis with the help of recent advanced biotechnology. High-resolution mass s...
Jingjing Ye, Hao Liu, Crystal Kirmiz, Carlito B. L...