Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Background: Proteins that evolve from a common ancestor can change functionality over time, and it is important to be able identify residues that cause this change. In this paper ...
MolProbity is a general-purpose web server offering quality validation for 3D structures of proteins, nucleic acids and complexes. It provides detailed all-atom contact analysis o...
Ian W. Davis, Andrew Leaver-Fay, Vincent B. Chen, ...
Background: In the post-genomic era, systems-level studies are being performed that seek to explain complex biological systems by integrating diverse resources from fields such as...
Julie D. Thompson, Arnaud Muller, Andrew M. Waterh...
In imaging genomics, there have been rapid advances in genome-wide, image-wide searches for genes that influence brain structure. Most efforts focus on univariate tests that treat...
Derrek P. Hibar, Jason L. Stein, Omid Kohannim, Ne...