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    BMCBI
    2008
    177views more  BMCBI 2008»
    Baseline Correction for NMR Spectroscopic Metabolomics Data Analysis
    13 years 10 months ago
    Baseline Correction for NMR Spectroscopic Metabolomics Data Analysis
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    Background: We propose a statistically principled baseline correction method, derived from a parametric smoothing model. It uses a score function to describe the key features of b...
    Yuanxin Xi, David M. Rocke
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    BMCBI
    2008
    110views more  BMCBI 2008»
    Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands
    13 years 10 months ago
    Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands
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    Background: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role...
    Wei Dai, Jens M. Teodoridis, Janet Graham, Constan...
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    BMCBI
    2007
    132views more  BMCBI 2007»
    On the analysis of glycomics mass spectrometry data via the regularized area under the ROC curve
    13 years 10 months ago
    On the analysis of glycomics mass spectrometry data via the regularized area under the ROC curve
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    Background: Novel molecular and statistical methods are in rising demand for disease diagnosis and prognosis with the help of recent advanced biotechnology. High-resolution mass s...
    Jingjing Ye, Hao Liu, Crystal Kirmiz, Carlito B. L...
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    BMCBI
    2008
    107views more  BMCBI 2008»
    Probe-specific mixed-model approach to detect copy number differences using multiplex ligation-dependent probe amplification (ML
    13 years 10 months ago
    Probe-specific mixed-model approach to detect copy number differences using multiplex ligation-dependent probe amplification (ML
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    Background: MLPA method is a potentially useful semi-quantitative method to detect copy number alterations in targeted regions. In this paper, we propose a method for the normaliz...
    Juan R. González, Josep L. Carrasco, Llu&ia...
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    BMCBI
    2006
    120views more  BMCBI 2006»
    An improved distance measure between the expression profiles linking co-expression and co-regulation in mouse
    13 years 10 months ago
    An improved distance measure between the expression profiles linking co-expression and co-regulation in mouse
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    Background: Many statistical algorithms combine microarray expression data and genome sequence data to identify transcription factor binding motifs in the low eukaryotic genomes. ...
    Ryung S. Kim, Hongkai Ji, Wing Hung Wong
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