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BMCBI
2008
172views more  BMCBI 2008»
13 years 7 months ago
Classification of drug molecules considering their IC50 values using mixed-integer linear programming based hyper-boxes method
Background: A priori analysis of the activity of drugs on the target protein by computational approaches can be useful in narrowing down drug candidates for further experimental t...
Pelin Armutlu, Muhittin Emre Ozdemir, Fadime Ü...
BMCBI
2008
95views more  BMCBI 2008»
13 years 7 months ago
Universal seeds for cDNA-to-genome comparison
Background: To meet the needs of gene annotation for newly sequenced organisms, optimized spaced seeds can be implemented into cross-species sequence alignment programs to accurat...
Leming Zhou, Jonathan Stanton, Liliana Florea
AAI
2006
215views more  AAI 2006»
13 years 7 months ago
Extensive Evaluation of Efficient NLP-Driven Text Classification
Extensive experimental evidence is required to study the impact of text categorization approaches on real data and to assess the performance within operational scenarios. In this ...
Roberto Basili, Alessandro Moschitti, Maria Teresa...
IJSTM
2008
77views more  IJSTM 2008»
13 years 7 months ago
The internal differentiation of the KIBS sector: empirical evidence from cluster analysis
: The sector of Knowledge-Intensive Business Services (KIBS) is characterised by high rates of firm fluctuation, rapid changes in technological progress (e.g., in the software indu...
Daniel Horgos, Andreas Koch
CORR
2007
Springer
128views Education» more  CORR 2007»
13 years 7 months ago
Model Selection Through Sparse Maximum Likelihood Estimation
We consider the problem of estimating the parameters of a Gaussian or binary distribution in such a way that the resulting undirected graphical model is sparse. Our approach is to...
Onureena Banerjee, Laurent El Ghaoui, Alexandre d'...