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SERVICES
2008
246views more  SERVICES 2008»
13 years 11 months ago
BioFlow: A Web-Based Declarative Workflow Language for Life Sciences
Scientific workflows in Life Sciences are usually complex, and use many online databases, analysis tools, publication repositories and customized computation intensive desktop sof...
Hasan M. Jamil, Bilal El-Hajj-Diab
BIOINFORMATICS
2010
127views more  BIOINFORMATICS 2010»
13 years 10 months ago
Analyzing taxonomic classification using extensible Markov models
Motivation: As next generation sequencing is rapidly adding new genomes, their correct placement in the taxonomy needs verification. However, the current methods for confirming cl...
Rao M. Kotamarti, Michael Hahsler, Douglas Raiford...
BMCBI
2008
130views more  BMCBI 2008»
13 years 10 months ago
A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Kevin Brick, Elisabetta Pizzi
BMCBI
2007
102views more  BMCBI 2007»
13 years 10 months ago
FlexOracle: predicting flexible hinges by identification of stable domains
Background: Protein motions play an essential role in catalysis and protein-ligand interactions, but are difficult to observe directly. A substantial fraction of protein motions i...
Samuel Flores, Mark Gerstein
BMCBI
2007
162views more  BMCBI 2007»
13 years 10 months ago
Three-Dimensional Phylogeny Explorer: Distinguishing paralogs, lateral transfer, and violation of "molecular clock" assumption w
Background: Construction and interpretation of phylogenetic trees has been a major research topic for understanding the evolution of genes. Increases in sequence data and complexi...
Namshin Kim, Christopher Lee