34 search results - page 5 / 7 » Regulation of metabolic networks by small molecule metabolit... |
BMCBI
2007
13 years 7 months ago
2007
Background: Manual curation of biological databases, an expensive and labor-intensive process, is essential for high quality integrated data. In this paper we report the implement...
NAR
2008
13 years 7 months ago
2008
The knowledge about interactions between proteins and small molecules is essential for the understanding of molecular and cellular functions. However, information on such interact...
BMCBI
2010
13 years 7 months ago
2010
Background: Various high throughput methods are available for detecting regulations at the level of transcription, translation or posttranslation (e.g. phosphorylation). Integrati...
BMCBI
2008
13 years 7 months ago
2008
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
BMCBI
2010
13 years 7 months ago
2010
Background: Metabolic pathway is a highly regulated network consisting of many metabolic reactions involving substrates, enzymes, and products, where substrates can be transformed...