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BMCBI
2005
153views more  BMCBI 2005»
13 years 7 months ago
A comparative review of estimates of the proportion unchanged genes and the false discovery rate
Background: In the analysis of microarray data one generally produces a vector of p-values that for each gene give the likelihood of obtaining equally strong evidence of change by...
Per Broberg
BMCBI
2008
167views more  BMCBI 2008»
13 years 7 months ago
Not proper ROC curves as new tool for the analysis of differentially expressed genes in microarray experiments
Background: Most microarray experiments are carried out with the purpose of identifying genes whose expression varies in relation with specific conditions or in response to enviro...
Stefano Parodi, Vito Pistoia, Marco Muselli
BMCBI
2005
101views more  BMCBI 2005»
13 years 7 months ago
TmaDB: a repository for tissue microarray data
Background: Tissue microarray (TMA) technology has been developed to facilitate large, genome-scale molecular pathology studies. This technique provides a high-throughput method f...
Archana Sharma-Oates, Philip Quirke, David R. West...
BMCBI
2008
124views more  BMCBI 2008»
13 years 7 months ago
Ontology-based, Tissue MicroArray oriented, image centered tissue bank
Background: Tissue MicroArray technique is becoming increasingly important in pathology for the validation of experimental data from transcriptomic analysis. This approach produce...
Federica Viti, Ivan Merelli, Andrea Caprera, Barba...
BMCBI
2007
146views more  BMCBI 2007»
13 years 7 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...