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BMCBI
2006
159views more  BMCBI 2006»
13 years 10 months ago
MultiSeq: unifying sequence and structure data for evolutionary analysis
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
Elijah Roberts, John Eargle, Dan Wright, Zaida Lut...
BMCBI
2006
140views more  BMCBI 2006»
13 years 10 months ago
SNP-PHAGE - High throughput SNP discovery pipeline
Background: Single nucleotide polymorphisms (SNPs) as defined here are single base sequence changes or short insertion/deletions between or within individuals of a given species. ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...
BMCBI
2006
86views more  BMCBI 2006»
13 years 10 months ago
Identification of QTLs controlling gene expression networks defined a priori
Background: Gene expression microarrays allow the quantification of transcript accumulation for many or all genes in a genome. This technology has been utilized for a range of inv...
Daniel J. Kliebenstein, Marilyn A. L. West, Hans v...
ECCC
2006
145views more  ECCC 2006»
13 years 9 months ago
Constraint satisfaction: a personal perspective
Attempts at classifying computational problems as polynomial time solvable, NP-complete, or belonging to a higher level in the polynomial hierarchy, face the difficulty of undecid...
Tomás Feder
BMCBI
2007
149views more  BMCBI 2007»
13 years 9 months ago
Identification of tissue-specific cis-regulatory modules based on interactions between transcription factors
Background: Evolutionary conservation has been used successfully to help identify cis-acting DNA regions that are important in regulating tissue-specific gene expression. Motivate...
Xueping Yu, Jimmy J. Lin, Donald J. Zack, Jiang Qi...