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BMCBI
2010
88views more  BMCBI 2010»
13 years 11 months ago
FastTagger: an efficient algorithm for genome-wide tag SNP selection using multi-marker linkage disequilibrium
Background: Human genome contains millions of common single nucleotide polymorphisms (SNPs) and these SNPs play an important role in understanding the association between genetic ...
Guimei Liu, Yue Wang, Limsoon Wong
BMCBI
2007
226views more  BMCBI 2007»
13 years 11 months ago
MiRFinder: an improved approach and software implementation for genome-wide fast microRNA precursor scans
Background: MicroRNAs (miRNAs) are recognized as one of the most important families of noncoding RNAs that serve as important sequence-specific post-transcriptional regulators of ...
Ting-Hua Huang, Bin Fan, Max F. Rothschild, Zhi-Li...
BMCBI
2006
107views more  BMCBI 2006»
13 years 11 months ago
A reinforced merging methodology for mapping unique peptide motifs in members of protein families
Background: Members of a protein family often have highly conserved sequences; most of these sequences carry identical biological functions and possess similar three-dimensional (...
Hao-Teng Chang, Tun-Wen Pai, Tan-Chi Fan, Bo-Han S...
BMCBI
2006
82views more  BMCBI 2006»
13 years 11 months ago
Profiling alternatively spliced mRNA isoforms for prostate cancer classification
Background: Prostate cancer is one of the leading causes of cancer illness and death among men in the United States and world wide. There is an urgent need to discover good biomar...
Chaolin Zhang, Hai-Ri Li, Jian-Bing Fan, Jessica W...
BMCBI
2007
127views more  BMCBI 2007»
13 years 11 months ago
Predicting the phenotypic effects of non-synonymous single nucleotide polymorphisms based on support vector machines
Background: Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occur approximately every 1000 bases in the overall human population. The no...
Jian Tian, Ningfeng Wu, Xuexia Guo, Jun Guo, Juhua...