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BMCBI
2007
147views more  BMCBI 2007»
15 years 6 months ago
Improved residue contact prediction using support vector machines and a large feature set
Background: Predicting protein residue-residue contacts is an important 2D prediction task. It is useful for ab initio structure prediction and understanding protein folding. In s...
Jianlin Cheng, Pierre Baldi
BMCBI
2008
204views more  BMCBI 2008»
15 years 6 months ago
EST2uni: an open, parallel tool for automated EST analysis and database creation, with a data mining web interface and microarra
Background: Expressed sequence tag (EST) collections are composed of a high number of single-pass, redundant, partial sequences, which need to be processed, clustered, and annotat...
Javier Forment, Francisco Gilabert Villamón...
BMCBI
2008
96views more  BMCBI 2008»
15 years 6 months ago
Novel methodology for construction and pruning of quasi-median networks
Background: Visualising the evolutionary history of a set of sequences is a challenge for molecular phylogenetics. One approach is to use undirected graphs, such as median network...
Sarah C. Ayling, Terence A. Brown
BMCBI
2007
112views more  BMCBI 2007»
15 years 6 months ago
Selecting dissimilar genes for multi-class classification, an application in cancer subtyping
Background: Gene expression microarray is a powerful technology for genetic profiling diseases and their associated treatments. Such a process involves a key step of biomarker ide...
Zhipeng Cai, Randy Goebel, Mohammad R. Salavatipou...
BMCBI
2007
103views more  BMCBI 2007»
15 years 6 months ago
eQTL Viewer: visualizing how sequence variation affects genome-wide transcription
Background: Expression Quantitative Trait Locus (eQTL) mapping methods have been used to identify the genetic basis of gene expression variations. To map eQTL, thousands of expres...
Wei Zou, David L. Aylor, Zhao-Bang Zeng
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