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HICSS
2006
IEEE
170views Biometrics» more  HICSS 2006»
14 years 2 months ago
A Complex Adaptive System Perspective of Enterprise Architecture in Electronic Government
Within the public sector, the deployment of enterprise architecture is often an attempt to address the decentralization/centralization relationships to improve the links between t...
Marijn Janssen, George Kuk
BMCBI
2006
130views more  BMCBI 2006»
13 years 8 months ago
An interactive visualization tool to explore the biophysical properties of amino acids and their contribution to substitution ma
Background: Quantitative descriptions of amino acid similarity, expressed as probabilistic models of evolutionary interchangeability, are central to many mainstream bioinformatic ...
Blazej Bulka, Marie desJardins, Stephen J. Freelan...
BMCBI
2011
13 years 2 months ago
The PathOlogist: An Automated Tool for Pathway-Centric Analysis
Background: The PathOlogist is a new tool designed to transform large sets of gene expression data into quantitative descriptors of pathway-level behavior. The tool aims to provid...
Sharon I. Greenblum, Sol Efroni, Carl F. Schaefer,...
BMCBI
2010
201views more  BMCBI 2010»
13 years 8 months ago
Analysis of X-ray Structures of Matrix Metalloproteinases via Chaotic Map Clustering
Background: Matrix metalloproteinases (MMPs) are well-known biological targets implicated in tumour progression, homeostatic regulation, innate immunity, impaired delivery of pro-...
Ilenia Giangreco, Orazio Nicolotti, Angelo Carotti...
BMCBI
2007
161views more  BMCBI 2007»
13 years 8 months ago
Efficient classification of complete parameter regions based on semidefinite programming
Background: Current approaches to parameter estimation are often inappropriate or inconvenient for the modelling of complex biological systems. For systems described by nonlinear ...
Lars Kuepfer, Uwe Sauer, Pablo A. Parrilo