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BMCBI
2007
13 years 9 months ago
2007
Background: Clustering methods are widely used on gene expression data to categorize genes with similar expression profiles. Finding an appropriate (dis)similarity measure is crit...
BMCBI
2007
2007
Penalized likelihood for sparse contingency tables with an application to full-length cDNA libraries
13 years 9 months ago
Background: The joint analysis of several categorical variables is a common task in many areas of biology, and is becoming central to systems biology investigations whose goal is ...
BMCBI
2008
13 years 9 months ago
2008
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
BMCBI
2007
13 years 9 months ago
2007
Background: By virtue of their shared ancestry, homologous sequences are similar in their structure and function. Consequently, multiple sequence alignments are routinely used to ...
BMCBI
2008
13 years 9 months ago
2008
Background: Genes that are co-expressed tend to be involved in the same biological process. However, co-expression is not a very reliable predictor of functional links between gen...