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BMCBI
2008
124views more  BMCBI 2008»
13 years 8 months ago
Alignment of protein structures in the presence of domain motions
Background: Structural alignment is an important step in protein comparison. Well-established methods exist for solving this problem under the assumption that the structures under...
Roberto Mosca, Barbara Brannetti, Thomas R. Schnei...
BMCBI
2006
203views more  BMCBI 2006»
13 years 8 months ago
Independent component analysis reveals new and biologically significant structures in micro array data
Background: An alternative to standard approaches to uncover biologically meaningful structures in micro array data is to treat the data as a blind source separation (BSS) problem...
Attila Frigyesi, Srinivas Veerla, David Lindgren, ...
BMCBI
2007
110views more  BMCBI 2007»
13 years 8 months ago
Interpretation of multiple probe sets mapping to the same gene in Affymetrix GeneChips
Background: Affymetrix GeneChip technology enables the parallel observations of tens of thousands of genes. It is important that the probe set annotations are reliable so that bio...
Maria A. Stalteri, Andrew P. Harrison
BMCBI
2005
151views more  BMCBI 2005»
13 years 8 months ago
stam - a Bioconductor compliant R package for structured analysis of microarray data
Background: Genome wide microarray studies have the potential to unveil novel disease entities. Clinically homogeneous groups of patients can have diverse gene expression profiles...
Claudio Lottaz, Rainer Spang
BMCBI
2005
79views more  BMCBI 2005»
13 years 8 months ago
Mathematical design of prokaryotic clone-based microarrays
Background: Clone-based microarrays, on which each spot represents a random genomic fragment, are a good alternative to open reading frame-based microarrays, especially for microo...
Bart Pieterse, Elisabeth J. Quirijns, Frank H. J. ...