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BMCBI
2008
135views more  BMCBI 2008»
13 years 10 months ago
Fregene: Simulation of realistic sequence-level data in populations and ascertained samples
Background: FREGENE simulates sequence-level data over large genomic regions in large populations. Because, unlike coalescent simulators, it works forwards through time, it allows...
Marc Chadeau-Hyam, Clive J. Hoggart, Paul F. O'Rei...
COGSCI
2008
139views more  COGSCI 2008»
13 years 10 months ago
A Computational Model of Early Argument Structure Acquisition
How children go about learning the general regularities that govern language, as well as keeping track of the exceptions to them, remains one of the challenging open questions in ...
Afra Alishahi, Suzanne Stevenson
BIOINFORMATICS
2006
101views more  BIOINFORMATICS 2006»
13 years 10 months ago
A lock-and-key model for protein-protein interactions
Motivation: Protein-protein interaction networks are one of the major post-genomic data sources available to molecular biologists. They provide a comprehensive view of the global ...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...
BMCBI
2006
135views more  BMCBI 2006»
13 years 10 months ago
iHAP - integrated haplotype analysis pipeline for characterizing the haplotype structure of genes
Background: The advent of genotype data from large-scale efforts that catalog the genetic variants of different populations have given rise to new avenues for multifactorial disea...
Chun Meng Song, Boon Huat Yeo, Erwin Tantoso, Yuch...
BMCBI
2007
126views more  BMCBI 2007»
13 years 9 months ago
Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...