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BIOINFORMATICS
2006
92views more  BIOINFORMATICS 2006»
13 years 8 months ago
What should be expected from feature selection in small-sample settings
Motivation: High-throughput technologies for rapid measurement of vast numbers of biological variables offer the potential for highly discriminatory diagnosis and prognosis; howev...
Chao Sima, Edward R. Dougherty
KDD
2008
ACM
104views Data Mining» more  KDD 2008»
14 years 9 months ago
Learning methods for lung tumor markerless gating in image-guided radiotherapy
In an idealized gated radiotherapy treatment, radiation is delivered only when the tumor is at the right position. For gated lung cancer radiotherapy, it is difficult to generate ...
Ying Cui, Jennifer G. Dy, Gregory C. Sharp, Brian ...
GECCO
2007
Springer
159views Optimization» more  GECCO 2007»
14 years 2 months ago
Evolutionary hypernetwork models for aptamer-based cardiovascular disease diagnosis
We present a biology-inspired probabilistic graphical model, called the hypernetwork model, and its application to medical diagnosis of disease. The hypernetwork models are a way ...
JungWoo Ha, Jae-Hong Eom, Sung-Chun Kim, Byoung-Ta...
GECCO
2006
Springer
162views Optimization» more  GECCO 2006»
14 years 5 days ago
Evolutionary learning with kernels: a generic solution for large margin problems
In this paper we embed evolutionary computation into statistical learning theory. First, we outline the connection between large margin optimization and statistical learning and s...
Ingo Mierswa
BMCBI
2008
118views more  BMCBI 2008»
13 years 8 months ago
Virtual screening of GPCRs: An in silico chemogenomics approach
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules is ...
Laurent Jacob, Brice Hoffmann, Véronique St...