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BMCBI
2006
117views more  BMCBI 2006»
13 years 7 months ago
A method for estimation of elasticities in metabolic networks using steady state and dynamic metabolomics data and linlog kineti
Background: Dynamic modeling of metabolic reaction networks under in vivo conditions is a crucial step in order to obtain a better understanding of the (dis)functioning of living ...
I. Emrah Nikerel, Wouter A. van Winden, Walter M. ...
BMCBI
2007
115views more  BMCBI 2007»
13 years 7 months ago
Correlation between structure and temperature in prokaryotic metabolic networks
Background: In recent years, an extensive characterization of network structures has been made in an effort to elucidate design principles of metabolic networks, providing valuabl...
Kazuhiro Takemoto, Jose C. Nacher, Tatsuya Akutsu
CIBCB
2008
IEEE
14 years 1 months ago
Temporal and structural analysis of biological networks in combination with microarray data
— We introduce a graph-based relational learning approach using graph-rewriting rules for temporal and structural analysis of biological networks changing over time. The analysis...
Chang Hun You, Lawrence B. Holder, Diane J. Cook
BMCBI
2007
97views more  BMCBI 2007»
13 years 7 months ago
A procedure for the estimation over time of metabolic fluxes in scenarios where measurements are uncertain and/or insufficient
Background: An indirect approach is usually used to estimate the metabolic fluxes of an organism: couple the available measurements with known biological constraints (e.g. stoichi...
Francisco Llaneras, Jesús Picó
BIOINFORMATICS
2007
117views more  BIOINFORMATICS 2007»
13 years 7 months ago
Mining biological networks for unknown pathways
Biological pathways provide significant insights on the interaction mechanisms of molecules. Presently, many essential pathways still remain unknown or incomplete for newly sequen...
Ali Cakmak, Gultekin Özsoyoglu