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BMCBI
2008
13 years 8 months ago
2008
Background: The identification of transcription factor binding sites is difficult since they are only a small number of nucleotides in size, resulting in large numbers of false po...
BMCBI
2007
13 years 8 months ago
2007
Background: Experimentally determined protein structures may contain errors and require validation. Conformational criteria based on the Ramachandran plot are mainly used to disti...
BMCBI
2008
13 years 8 months ago
2008
Background: Recent genome wide transcription factor binding site or chromatin modification mapping analysis techniques, such as chromatin immunoprecipitation (ChIP) linked to DNA ...
BMCBI
2008
13 years 8 months ago
2008
Background: The recent availability of complete sequences for numerous closely related bacterial genomes opens up new challenges in comparative genomics. Several methods have been...
BMCBI
2008
13 years 8 months ago
2008
Background: It has repeatedly been shown that interacting protein families tend to have similar phylogenetic trees. These similarities can be used to predicting the mapping betwee...