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122
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BMCBI
2004
15 years 4 months ago
2004
Background: Tissue Microarrays (TMAs) have emerged as a powerful tool for examining the distribution of marker molecules in hundreds of different tissues displayed on a single sli...
153
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BMCBI
2004
15 years 4 months ago
2004
Background: Several aspects of microarray data analysis are dependent on identification of genes expressed at or near the limits of detection. For example, regression-based normal...
135
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BMCBI
2004
15 years 4 months ago
2004
Background: Metabolic pathway analysis has been recognized as a central approach to the structural analysis of metabolic networks. The concept of elementary (flux) modes provides ...
177
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BMCBI
2004
15 years 4 months ago
2004
Background: The function of a novel gene product is typically predicted by transitive assignment of annotation from similar sequences. We describe a novel method, GOtcha, for pred...
151
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BMCBI
2004
15 years 4 months ago
2004
Background: A number of completely sequenced eukaryotic genome data are available in the public domain. Eukaryotic genes are either 'intron containing' or 'intronle...