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127
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BMCBI
2007
175views more  BMCBI 2007»
15 years 3 months ago
CLUSS: Clustering of protein sequences based on a new similarity measure
Background: The rapid burgeoning of available protein data makes the use of clustering within families of proteins increasingly important. The challenge is to identify subfamilies...
Abdellali Kelil, Shengrui Wang, Ryszard Brzezinski...
128
Voted
BMCBI
2008
145views more  BMCBI 2008»
15 years 3 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
125
Voted
BMCBI
2010
100views more  BMCBI 2010»
15 years 3 months ago
Scaffold filling, contig fusion and comparative gene order inference
Background: There has been a trend in increasing the phylogenetic scope of genome sequencing without finishing the sequence of the genome. Increasing numbers of genomes are being ...
Adriana Muñoz, Chunfang Zheng, Qian Zhu, Vi...
128
Voted
BMCBI
2007
165views more  BMCBI 2007»
15 years 3 months ago
Direct maximum parsimony phylogeny reconstruction from genotype data
Background: Maximum parsimony phylogenetic tree reconstruction from genetic variation data is a fundamental problem in computational genetics with many practical applications in p...
Srinath Sridhar, Fumei Lam, Guy E. Blelloch, R. Ra...
139
Voted
COOPIS
2004
IEEE
15 years 7 months ago
Refresco: Improving Query Performance Through Freshness Control in a Database Cluster
Abstract. We consider the use of a cluster system for managing autonomous databases. In order to improve the performance of read-only queries, we strive to exploit user requirement...
Cécile Le Pape, Stéphane Ganç...