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BMCBI
2007
80views more  BMCBI 2007»
13 years 7 months ago
A network perspective on the topological importance of enzymes and their phylogenetic conservation
Background: A metabolic network is the sum of all chemical transformations or reactions in the cell, with the metabolites being interconnected by enzyme-catalyzed reactions. Many ...
Wei-chung Liu, Wen-hsien Lin, Andrew J. Davis, Fer...
BMCBI
2011
12 years 11 months ago
PhyloMap: an algorithm for visualizing relationships of large sequence data sets and its application to the influenza A virus ge
Background: Results of phylogenetic analysis are often visualized as phylogenetic trees. Such a tree can typically only include up to a few hundred sequences. When more than a few...
Jiajie Zhang, Amir Madany Mamlouk, Thomas Martinet...
NAR
2007
109views more  NAR 2007»
13 years 7 months ago
GeneTrees: a phylogenomics resource for prokaryotes
The GeneTrees phylogenomics system pursues comparative genomic analyses from the perspective of gene phylogenies for individual genes. The GeneTrees project has the goal of provid...
Yuying Tian, Allan W. Dickerman
BMCBI
2007
162views more  BMCBI 2007»
13 years 7 months ago
Three-Dimensional Phylogeny Explorer: Distinguishing paralogs, lateral transfer, and violation of "molecular clock" assumption w
Background: Construction and interpretation of phylogenetic trees has been a major research topic for understanding the evolution of genes. Increases in sequence data and complexi...
Namshin Kim, Christopher Lee
BMCBI
2007
147views more  BMCBI 2007»
13 years 7 months ago
MaxAlign: maximizing usable data in an alignment
Background: The presence of gaps in an alignment of nucleotide or protein sequences is often an inconvenience for bioinformatical studies. In phylogenetic and other analyses, for ...
Rodrigo Gouveia-Oliveira, Peter Wad Sackett, Ander...