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» Resolution of large and small differences in gene expression...
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BMCBI
2011
12 years 10 months ago
Proportion statistics to detect differentially expressed genes: a comparison with log-ratio statistics
Background: In genetic transcription research, gene expression is typically reported in a test sample relative to a reference sample. Laboratory assays that measure gene expressio...
Tracy L. Bergemann, Jason Wilson
BMCBI
2007
132views more  BMCBI 2007»
13 years 6 months ago
Analysis of probe level patterns in Affymetrix microarray data
Background: Microarrays have been used extensively to analyze the expression profiles for thousands of genes in parallel. Most of the widely used methods for analyzing Affymetrix ...
Alexander C. Cambon, Abdelnaby Khalyfa, Nigel G. F...
BMCBI
2006
125views more  BMCBI 2006»
13 years 6 months ago
Evaluating different methods of microarray data normalization
Background: With the development of DNA hybridization microarray technologies, nowadays it is possible to simultaneously assess the expression levels of thousands to tens of thous...
André Fujita, João Ricardo Sato, Leo...
BMCBI
2005
140views more  BMCBI 2005»
13 years 6 months ago
Dissecting systems-wide data using mixture models: application to identify affected cellular processes
Background: Functional analysis of data from genome-scale experiments, such as microarrays, requires an extensive selection of differentially expressed genes. Under many condition...
J. Peter Svensson, Renée X. de Menezes, Ing...
CSB
2005
IEEE
156views Bioinformatics» more  CSB 2005»
14 years 10 days ago
A Robust Meta-classification Strategy for Cancer Diagnosis from Gene Expression Data
One of the major challenges in cancer diagnosis from microarray data is to develop robust classification models which are independent of the analysis techniques used and can combi...
Gabriela Alexe, Gyan Bhanot, Babu Venkataraghavan,...