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ICARIS
2010
Springer
13 years 10 months ago
Defining a Simulation Strategy for Cancer Immunocompetence
Although there are various types of cancer treatments, none of these currently take into account the effect of ageing of the immune system and hence altered responses to cancer. R...
Grazziela P. Figueredo, Uwe Aickelin
BMCBI
2010
118views more  BMCBI 2010»
13 years 9 months ago
Testing for mean and correlation changes in microarray experiments: an application for pathway analysis
Background: Microarray experiments examine the change in transcript levels of tens of thousands of genes simultaneously. To derive meaningful data, biologists investigate the resp...
Mayer Alvo, Zhongzhu Liu, Andrew Williams, Carole ...
BMCBI
2007
121views more  BMCBI 2007»
13 years 9 months ago
Development of an epitope conservancy analysis tool to facilitate the design of epitope-based diagnostics and vaccines
Background: In an epitope-based vaccine setting, the use of conserved epitopes would be expected to provide broader protection across multiple strains, or even species, than epito...
Huynh-Hoa Bui, John Sidney, Wei Li, Nicholas Fusse...
BMCBI
2005
201views more  BMCBI 2005»
13 years 9 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
TRS
2008
13 years 9 months ago
The Neurophysiological Bases of Cognitive Computation Using Rough Set Theory
A popular view is that the brain works in a similar way to a digital computer or a Universal Turing Machine by processing symbols. Psychophysical experiments and our amazing capabi...
Andrzej W. Przybyszewski