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BMCBI
2005
134views more  BMCBI 2005»
13 years 10 months ago
Ancestral sequence alignment under optimal conditions
Background: Multiple genome alignment is an important problem in bioinformatics. An important subproblem used by many multiple alignment approaches is that of aligning two multipl...
Alexander K. Hudek, Daniel G. Brown 0001
BMCBI
2005
94views more  BMCBI 2005»
13 years 10 months ago
Visualization-based discovery and analysis of genomic aberrations in microarray data
Background: Chromosomal copy number changes (aneuploidies) play a key role in cancer progression and molecular evolution. These copy number changes can be studied using microarray...
Chad L. Myers, Xing Chen, Olga G. Troyanskaya
BMCBI
2005
250views more  BMCBI 2005»
13 years 10 months ago
FiatFlux - a software for metabolic flux analysis from 13C-glucose experiments
Background: Quantitative knowledge of intracellular fluxes is important for a comprehensive characterization of metabolic networks and their functional operation. In contrast to d...
Nicola Zamboni, Eliane Fischer, Uwe Sauer
JCB
2007
144views more  JCB 2007»
13 years 10 months ago
Statistical Estimation of Statistical Mechanical Models: Helix-Coil Theory and Peptide Helicity Prediction
Analysis of biopolymer sequences and structures generally adopts one of two approaches: use of detailed biophysical theoretical models of the system with experimentally-determined...
Scott C. Schmidler, Joseph E. Lucas, Terrence G. O...
TMI
2008
91views more  TMI 2008»
13 years 10 months ago
MRI-Based Automated Computer Classification of Probable AD Versus Normal Controls
Automated computer classification (ACC) techniques are needed to facilitate physician's diagnosis of complex diseases in individual patients. We provide an example of ACC usin...
Simon Duchesne, A. Caroli, C. Geroldi, Christian B...