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» Retrieval of 3D protein structures
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NAR
2008
122views more  NAR 2008»
13 years 11 months ago
SIMAP - structuring the network of protein similarities
Protein sequences are the most important source of evolutionary and functional information for new proteins. In order to facilitate the computationally intensive tasks of sequence...
Thomas Rattei, Patrick Tischler, Roland Arnold, Fr...
BMCBI
2010
95views more  BMCBI 2010»
13 years 11 months ago
Quantifying the relationship between sequence and three-dimensional structure conservation in RNA
Background: In recent years, the number of available RNA structures has rapidly grown reflecting the increased interest on RNA biology. Similarly to the studies carried out two de...
Emidio Capriotti, Marc A. Martí-Renom
BMCBI
2007
59views more  BMCBI 2007»
13 years 11 months ago
Environment specific substitution tables for thermophilic proteins
Background: Thermophilic organisms are able to live at high temperatures ranging from 50 to > 100°C. Their proteins must be sufficiently stable to function under these extreme...
K. Mizuguchi, M. Sele, Maria Vittoria Cubellis
PAKDD
2005
ACM
180views Data Mining» more  PAKDD 2005»
14 years 4 months ago
Conditional Random Fields for Transmembrane Helix Prediction
Abstract. It is estimated that 20% of genes in the human genome encode for integral membrane proteins (IMPs) and some estimates are much higher. IMPs control a broad range of event...
Lior Lukov, Sanjay Chawla, W. Bret Church
BMCBI
2005
138views more  BMCBI 2005»
13 years 10 months ago
Detailed protein sequence alignment based on Spectral Similarity Score (SSS)
Background: The chemical property and biological function of a protein is a direct consequence of its primary structure. Several algorithms have been developed which determine ali...
Kshitiz Gupta, Dina Thomas, S. V. Vidya, K. V. Ven...