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» Retrieval of 3D protein structures
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BMCBI
2010
116views more  BMCBI 2010»
13 years 11 months ago
A hybrid approach to protein folding problem integrating constraint programming with local search
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
Abu Zafer M. Dayem Ullah, Kathleen Steinhöfel
JCB
2006
215views more  JCB 2006»
13 years 11 months ago
Protein Fold Recognition Using Segmentation Conditional Random Fields (SCRFs)
Protein fold recognition is an important step towards understanding protein three-dimensional structures and their functions. A conditional graphical model, i.e., segmentation con...
Yan Liu 0002, Jaime G. Carbonell, Peter Weigele, V...
ISBI
2002
IEEE
14 years 11 months ago
Image content-based retrieval and automated interpretation of fluorescence microscope images via the protein subcellular locatio
We describe the Protein Subcellular Location Image Database (PSLID), which collects and structures 2-D through 5-D fluorescence microscope images, annotations, and derived feature...
Kai Huang, Jennifer Lin, James A. Gajnak, Robert F...
BIOINFORMATICS
2006
134views more  BIOINFORMATICS 2006»
13 years 11 months ago
HaptenDB: a comprehensive database of haptens, carrier proteins and anti-hapten antibodies
The key requirement for successful immunochemical assay is the availability of antibodies with high specificity and desired affinity. Small molecules, when used as haptens, are no...
Mahender Kumar Singh, Shilpy Srivastava, G. P. S. ...
JIB
2006
106views more  JIB 2006»
13 years 11 months ago
A structural keystone for drug design
3D-structures of proteins and potential ligands are the cornerstones of rational drug design. The first brick to build upon is selecting a protein target and finding out whether b...
Kristian Rother, Mathias Dunkel, Elke Michalsky, S...