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» Retrieval of 3D protein structures
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BMCBI
2010
123views more  BMCBI 2010»
13 years 10 months ago
A new protein binding pocket similarity measure based on comparison of clouds of atoms in 3D: application to ligand prediction
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...
Brice Hoffmann, Mikhail Zaslavskiy, Jean-Philippe ...
PCM
2010
Springer
179views Multimedia» more  PCM 2010»
13 years 8 months ago
3D Similarity Search Using a Weighted Structural Histogram Representation
A fast and robust 3D retrieval method is proposed based on a novel weighted structural histogram representation. Our method has the following steps: 1) adaptively segment any 3D sh...
Tong Lu, Rongjun Gao, Tuantuan Wang, Yubin Yang
CSB
2005
IEEE
140views Bioinformatics» more  CSB 2005»
14 years 3 months ago
TPR Packing Analysis and 3D Modeling for the HAT Domain of Human Crooked Neck Protein
Human crooked neck protein (hcrn) containing 17 HAT or TPR repeats plays a role in pre-mRNA processing. Conserved residues in the TPR consensus sequence of 34 aa were found at hel...
Zhenglin Hou, Cunxi Wang, Odd-Arne Olsen
BMCBI
2007
116views more  BMCBI 2007»
13 years 9 months ago
Clustering protein environments for function prediction: finding PROSITE motifs in 3D
Background: Structural genomics initiatives are producing increasing numbers of threedimensional (3D) structures for which there is little functional information. Structure-based ...
Sungroh Yoon, Jessica C. Ebert, Eui-Young Chung, G...
BMCBI
2005
152views more  BMCBI 2005»
13 years 9 months ago
An ant colony optimisation algorithm for the 2D and 3D hydrophobic polar protein folding problem
Background: The protein folding problem is a fundamental problems in computational molecular biology and biochemical physics. Various optimisation methods have been applied to for...
Alena Shmygelska, Holger H. Hoos