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CSB
2003
IEEE
14 years 25 days ago
Initial Large-scale Exploration of Protein-protein Interactions in Human Brain
Study of protein interaction networks is crucial to post-genomic systems biology. Aided by highthroughput screening technologies, biologists are rapidly accumulating protein-prote...
Jake Yue Chen, Andrey Y. Sivachenko, Russell Bell,...
BIOINFORMATICS
2006
101views more  BIOINFORMATICS 2006»
13 years 7 months ago
A lock-and-key model for protein-protein interactions
Motivation: Protein-protein interaction networks are one of the major post-genomic data sources available to molecular biologists. They provide a comprehensive view of the global ...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...
BMCBI
2004
98views more  BMCBI 2004»
13 years 7 months ago
STING Millennium Suite: integrated software for extensive analyses of 3d structures of proteins and their complexes
Background: The integration of many aspects of protein/DNA structure analysis is an important requirement for software products in general area of structural bioinformatics. In fa...
Roberto H. Higa, Roberto C. Togawa, Arnaldo J. Mon...
BMCBI
2008
118views more  BMCBI 2008»
13 years 7 months ago
Inferring transcriptional compensation interactions in yeast via stepwise structure equation modeling
Background: With the abundant information produced by microarray technology, various approaches have been proposed to infer transcriptional regulatory networks. However, few appro...
Grace S. Shieh, Chung-Ming Chen, Ching-Yun Yu, Jui...
BMCBI
2010
174views more  BMCBI 2010»
13 years 7 months ago
The effect of prior assumptions over the weights in BayesPI with application to study protein-DNA interactions from ChIP-based h
Background: To further understand the implementation of hyperparameters re-estimation technique in Bayesian hierarchical model, we added two more prior assumptions over the weight...
Junbai Wang