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BMCBI
2008
128views more  BMCBI 2008»
13 years 7 months ago
Finding sequence motifs with Bayesian models incorporating positional information: an application to transcription factor bindin
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
Nak-Kyeong Kim, Kannan Tharakaraman, Leonardo Mari...
BMCBI
2010
161views more  BMCBI 2010»
13 years 7 months ago
BPDA - A Bayesian peptide detection algorithm for mass spectrometry
Background: Mass spectrometry (MS) is an essential analytical tool in proteomics. Many existing algorithms for peptide detection are based on isotope template matching and usually...
Youting Sun, Jianqiu Zhang, Ulisses Braga-Neto, Ed...
BMCBI
2007
102views more  BMCBI 2007»
13 years 7 months ago
A comprehensive system for evaluation of remote sequence similarity detection
Background: Accurate and sensitive performance evaluation is crucial for both effective development of better structure prediction methods based on sequence similarity, and for th...
Yuan Qi, Ruslan Sadreyev, Yong Wang, Bong-Hyun Kim...
BMCBI
2008
122views more  BMCBI 2008»
13 years 7 months ago
Determining gene expression on a single pair of microarrays
Background: In microarray experiments the numbers of replicates are often limited due to factors such as cost, availability of sample or poor hybridization. There are currently fe...
Robert W. Reid, Anthony A. Fodor
COR
2010
121views more  COR 2010»
13 years 7 months ago
A multi-objective approach for robust airline scheduling
We present a memetic approach for multi-objective improvement of robustness influencing features (called robustness objectives) in airline schedules. Improvement of the objectives...
Edmund K. Burke, Patrick De Causmaecker, Geert De ...