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» Robust test method for time-course microarray experiments
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JCP
2006
157views more  JCP 2006»
13 years 7 months ago
CF-GeNe: Fuzzy Framework for Robust Gene Regulatory Network Inference
Most Gene Regulatory Network (GRN) studies ignore the impact of the noisy nature of gene expression data despite its significant influence upon inferred results. This paper present...
Muhammad Shoaib B. Sehgal, Iqbal Gondal, Laurence ...
BMCBI
2004
113views more  BMCBI 2004»
13 years 7 months ago
Leveraging two-way probe-level block design for identifying differential gene expression with high-density oligonucleotide array
Background: To identify differentially expressed genes across experimental conditions in oligonucleotide microarray experiments, existing statistical methods commonly use a summar...
Leah Barrera, Chris Benner, Yong-Chuan Tao, Elizab...
BMCBI
2005
88views more  BMCBI 2005»
13 years 7 months ago
Using large-scale perturbations in gene network reconstruction
Background: Recent analysis of the yeast gene network shows that most genes have few inputs, indicating that enumerative gene reconstruction methods are both useful and computatio...
Thomas MacCarthy, Andrew Pomiankowski, Robert Seym...
BIOCOMP
2006
13 years 9 months ago
Marker Gene Selection Evaluation in Brain Tumor Patients Using Parallel Coordinates
Based on microarray gene expression datasets, many statistical methods have been proposed to locate the significant differentially expressed genes (marker genes) among different sa...
Atiq Islam, Khan M. Iftekharuddin, David J. Russom...
BMCBI
2011
13 years 2 months ago
Support vector machines-based identification of alternative splicing in Arabidopsis thaliana from whole-genome tiling arrays
Background: Alternative splicing (AS) is a process which generates several distinct mRNA isoforms from the same gene by splicing different portions out of the precursor transcript...
Johannes Eichner, Georg Zeller, Sascha Laubinger, ...