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BMCBI
2010
107views more  BMCBI 2010»
13 years 8 months ago
Conditional random pattern model for copy number aberration detection
Background: DNA copy number aberration (CNA) is very important in the pathogenesis of tumors and other diseases. For example, CNAs may result in suppression of anti-oncogenes and ...
Fuhai Li, Xiaobo Zhou, Wanting Huang, Chung-Che Ch...
BMCBI
2010
102views more  BMCBI 2010»
13 years 8 months ago
Quantized correlation coefficient for measuring reproducibility of ChIP-chip data
Background: Chromatin immunoprecipitation followed by microarray hybridization (ChIP-chip) is used to study protein-DNA interactions and histone modifications on a genome-scale. T...
Shouyong Peng, Mitzi I. Kuroda, Peter J. Park
BMCBI
2007
149views more  BMCBI 2007»
13 years 8 months ago
A unified framework for finding differentially expressed genes from microarray experiments
Background: This paper presents a unified framework for finding differentially expressed genes (DEGs) from the microarray data. The proposed framework has three interrelated modul...
Jahangheer S. Shaik, Mohammed Yeasin
BMCBI
2008
95views more  BMCBI 2008»
13 years 8 months ago
Unsupervised reduction of random noise in complex data by a row-specific, sorted principal component-guided method
Background: Large biological data sets, such as expression profiles, benefit from reduction of random noise. Principal component (PC) analysis has been used for this purpose, but ...
Joseph W. Foley, Fumiaki Katagiri
CORR
2010
Springer
130views Education» more  CORR 2010»
13 years 8 months ago
Stable Principal Component Pursuit
In this paper, we study the problem of recovering a low-rank matrix (the principal components) from a highdimensional data matrix despite both small entry-wise noise and gross spar...
Zihan Zhou, Xiaodong Li, John Wright, Emmanuel J. ...