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BMCBI
2007
109views more  BMCBI 2007»
13 years 6 months ago
Computational RNA secondary structure design: empirical complexity and improved methods
Background: We investigate the empirical complexity of the RNA secondary structure design problem, that is, the scaling of the typical difficulty of the design task for various cl...
Rosalía Aguirre-Hernández, Holger H....
DM
2008
94views more  DM 2008»
13 years 6 months ago
Discrete transformation hypergroups and transformation hypergroups with phase tolerance space
Tolerance spaces and algebraic structures with compatible tolerances play an important role in contemporary algebra and their applications. In this contribution we are presenting ...
Sárka Hosková, Jan Chvalina
ALMOB
2006
102views more  ALMOB 2006»
13 years 6 months ago
Mining, compressing and classifying with extensible motifs
Background: Motif patterns of maximal saturation emerged originally in contexts of pattern discovery in biomolecular sequences and have recently proven a valuable notion also in t...
Alberto Apostolico, Matteo Comin, Laxmi Parida
BMCBI
2006
127views more  BMCBI 2006»
13 years 6 months ago
Automatic discovery of cross-family sequence features associated with protein function
Background: Methods for predicting protein function directly from amino acid sequences are useful tools in the study of uncharacterised protein families and in comparative genomic...
Markus Brameier, Josien Haan, Andrea Krings, Rober...
BMCBI
2006
122views more  BMCBI 2006»
13 years 6 months ago
A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks
Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...
Holger Conzelmann, Julio Saez-Rodriguez, Thomas Sa...