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BMCBI
2004
88views more  BMCBI 2004»
13 years 7 months ago
Coronavirus 3CLpro proteinase cleavage sites: Possible relevance to SARS virus pathology
Background: Despite the passing of more than a year since the first outbreak of Severe Acute Respiratory Syndrome (SARS), efficient counter-measures are still few and many believe...
Lars Kiemer, Ole Lund, Søren Brunak, Nikola...
BMCBI
2002
101views more  BMCBI 2002»
13 years 7 months ago
Total sequence decomposition distinguishes functional modules, "molegos" in apurinic/apyrimidinic endonucleases
Background: Total sequence decomposition, using the web-based MASIA tool, identifies areas of conservation in aligned protein sequences. By structurally annotating these motifs, t...
Catherine H. Schein, Numan Özgün, Tadahi...
GECCO
2005
Springer
218views Optimization» more  GECCO 2005»
14 years 1 months ago
Particle swarm optimization for analysis of mass spectral serum profiles
Serum profiling using mass spectrometry is an emerging technology with a great potential to provide biomarkers for complex diseases such as cancer. However, protein profiles obtai...
Habtom W. Ressom, Rency S. Varghese, Daniel Saha, ...
BIB
2008
101views more  BIB 2008»
13 years 7 months ago
Information quality in proteomics
Proteomics, the study of the protein complement of a biological system, is generating increasing quantities of data from rapidly developing technologies employed in a variety of d...
David Stead, Norman W. Paton, Paolo Missier, Suzan...
NAR
2006
84views more  NAR 2006»
13 years 7 months ago
Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases
Individual zinc finger (ZF) domains that recognize DNA triplets with high specificity and affinity can be used to create designer transcription factors and nucleases that are spec...
Jeffrey G. Mandell, Carlos F. Barbas III