451 search results - page 70 / 91 » SAT-based protein design |
BMCBI
2007
13 years 7 months ago
2007
Background: Transcription factors (TFs) are key regulatory proteins that enhance or repress the transcriptional rate of their target genes by binding to specific promoter regions ...
BMCBI
2007
13 years 7 months ago
2007
High-throughput methods can directly detect the set of interacting proteins in yeast but the results are often incomplete and exhibit high false positive and false negative rates....
BMCBI
2005
13 years 7 months ago
2005
Background: Gene duplication and gene loss during the evolution of eukaryotes have hindered attempts to estimate phylogenies and divergence times of species. Although current meth...
JCB
2007
13 years 7 months ago
2007
Analysis of biopolymer sequences and structures generally adopts one of two approaches: use of detailed biophysical theoretical models of the system with experimentally-determined...
BMCBI
2005
13 years 7 months ago
2005
Background: In the context of the BioCreative competition, where training data were very sparse, we investigated two complementary tasks: 1) given a Swiss-Prot triplet, containing...