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» SIMAGE: simulation of DNA-microarray gene expression data
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BMCBI
2007
127views more  BMCBI 2007»
13 years 7 months ago
Characterization and simulation of cDNA microarray spots using a novel mathematical model
Background: The quality of cDNA microarray data is crucial for expanding its application to other research areas, such as the study of gene regulatory networks. Despite the fact t...
Hye Young Kim, Seo Eun Lee, Min Jung Kim, Jin Il H...
BMCBI
2006
110views more  BMCBI 2006»
13 years 7 months ago
Design of a combinatorial DNA microarray for protein-DNA interaction studies
Background: Discovery of precise specificity of transcription factors is an important step on the way to understanding the complex mechanisms of gene regulation in eukaryotes. Rec...
Julian Mintseris, Michael B. Eisen
BMCBI
2004
139views more  BMCBI 2004»
13 years 7 months ago
Resolution of large and small differences in gene expression using models for the Bayesian analysis of gene expression levels an
Background: The detection of small yet statistically significant differences in gene expression in spotted DNA microarray studies is an ongoing challenge. Meeting this challenge r...
Jeffrey P. Townsend
WILF
2007
Springer
147views Fuzzy Logic» more  WILF 2007»
14 years 1 months ago
Fuzzy Ensemble Clustering for DNA Microarray Data Analysis
Two major problems related the unsupervised analysis of gene expression data are represented by the accuracy and reliability of the discovered clusters, and by the biological fact ...
Roberto Avogadri, Giorgio Valentini
BMCBI
2007
130views more  BMCBI 2007»
13 years 7 months ago
A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...