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» SIMAP - structuring the network of protein similarities
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BMCBI
2007
101views more  BMCBI 2007»
13 years 7 months ago
Relationship between insertion/deletion (indel) frequency of proteins and essentiality
Background: In a previous study, we demonstrated that some essential proteins from pathogenic organisms contained sizable insertions/deletions (indels) when aligned to human prote...
Simon K. Chan, Michael Hsing, Fereydoun Hormozdiar...
CSB
2005
IEEE
118views Bioinformatics» more  CSB 2005»
14 years 1 months ago
A Protein Interaction Verification System Based on a Neural Network Algorithm
Large amounts of protein-protein interaction data have been identified using various genome-scale screening techniques. Although interaction data is a valuable resource, high-thro...
Min Su Lee, Seung-Soo Park, Min Kyung Kim
BMCBI
2006
147views more  BMCBI 2006»
13 years 7 months ago
QPath: a method for querying pathways in a protein-protein interaction network
Background: Sequence comparison is one of the most prominent tools in biological research, and is instrumental in studying gene function and evolution. The rapid development of hi...
Tomer Shlomi, Daniel Segal, Eytan Ruppin, Roded Sh...
BIBE
2005
IEEE
154views Bioinformatics» more  BIBE 2005»
14 years 1 months ago
Effective Pre-Processing Strategies for Functional Clustering of a Protein-Protein Interactions Network
In this article we present novel preprocessing techniques, based on topological measures of the network, to identify clusters of proteins from Protein-protein interaction (PPI) ne...
Duygu Ucar, Srinivasan Parthasarathy, Sitaram Asur...
CSB
2005
IEEE
139views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Predicting gene function by combining expression and interaction data
In this study we combined the spurious protein interaction data from the Database of Interacting Proteins with the recently published gene expression data of S. cerevisiae grown w...
Rogier J. P. van Berlo, Lodewyk F. A. Wessels, S. ...