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BMCBI
2010
106views more  BMCBI 2010»
13 years 7 months ago
A novel approach for haplotype-based association analysis using family data
Background: Haplotype-based approaches have been extensively studied for case-control association mapping in recent years. It has been shown that haplotype methods can provide mor...
Yixuan Chen, Xin Li, Jing Li
BMCBI
2007
237views more  BMCBI 2007»
13 years 7 months ago
FLAME, a novel fuzzy clustering method for the analysis of DNA microarray data
Background: Data clustering analysis has been extensively applied to extract information from gene expression profiles obtained with DNA microarrays. To this aim, existing cluster...
Limin Fu, Enzo Medico
BMCBI
2007
161views more  BMCBI 2007»
13 years 7 months ago
Efficient classification of complete parameter regions based on semidefinite programming
Background: Current approaches to parameter estimation are often inappropriate or inconvenient for the modelling of complex biological systems. For systems described by nonlinear ...
Lars Kuepfer, Uwe Sauer, Pablo A. Parrilo
BMCBI
2010
151views more  BMCBI 2010»
13 years 7 months ago
Using diffusion distances for flexible molecular shape comparison
Background: Many molecules are flexible and undergo significant shape deformation as part of their function, and yet most existing molecular shape comparison (MSC) methods treat t...
Yu-Shen Liu, Qi Li, Guo-Qin Zheng, Karthik Ramani,...
BMCBI
2008
114views more  BMCBI 2008»
13 years 7 months ago
Visualization of large influenza virus sequence datasets using adaptively aggregated trees with sampling-based subscale represen
Background: With the amount of influenza genome sequence data growing rapidly, researchers need machine assistance in selecting datasets and exploring the data. Enhanced visualiza...
Leonid Zaslavsky, Yiming Bao, Tatiana A. Tatusova