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BMCBI
2006
166views more  BMCBI 2006»
13 years 10 months ago
bioNMF: a versatile tool for non-negative matrix factorization in biology
Background: In the Bioinformatics field, a great deal of interest has been given to Non-negative matrix factorization technique (NMF), due to its capability of providing new insig...
Alberto D. Pascual-Montano, Pedro Carmona-Saez, Mo...
BMCBI
2006
118views more  BMCBI 2006»
13 years 10 months ago
Statistical analysis of an RNA titration series evaluates microarray precision and sensitivity on a whole-array basis
Background: Concerns are often raised about the accuracy of microarray technologies and the degree of cross-platform agreement, but there are yet no methods which can unambiguousl...
Andrew J. Holloway, Alicia Oshlack, Dileepa S. Diy...
ENVSOFT
2006
125views more  ENVSOFT 2006»
13 years 10 months ago
Sensitivity analysis based on regional splits and regression trees (SARS-RT)
A global sensitivity analysis with regional properties is introduced. This method is demonstrated on two synthetic and one hydraulic example. It can be shown that an uncertainty a...
Florian Pappenberger, Ion Iorgulescu, Keith J. Bev...
BMCBI
2007
163views more  BMCBI 2007»
13 years 10 months ago
Use of genomic DNA control features and predicted operon structure in microarray data analysis: ArrayLeaRNA - a Bayesian approac
Background: Microarrays are widely used for the study of gene expression; however deciding on whether observed differences in expression are significant remains a challenge. Resul...
Carmen Pin, Mark Reuter
BMCBI
2007
147views more  BMCBI 2007»
13 years 10 months ago
Bias in random forest variable importance measures: Illustrations, sources and a solution
Variable importance measures for random forests have been receiving increased attention as a means of variable selection in many classification tasks in bioinformatics and relate...
Carolin Strobl, Anne-Laure Boulesteix, Achim Zeile...