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BMCBI
2005
86views more  BMCBI 2005»
13 years 7 months ago
Confirmation of human protein interaction data by human expression data
Background: With microarray technology the expression of thousands of genes can be measured simultaneously. It is well known that the expression levels of genes of interacting pro...
Andreas Hahn, Jörg Rahnenführer, Priti T...
NAR
2007
65views more  NAR 2007»
13 years 7 months ago
STRING 7 - recent developments in the integration and prediction of protein interactions
Information on protein–protein interactions is still mostly limited to a small number of model organisms, and originates from a wide variety of experimental and computational te...
Christian von Mering, Lars Juhl Jensen, Michael Ku...
BMCBI
2005
97views more  BMCBI 2005»
13 years 7 months ago
Phylogenetic reconstruction of ancestral character states for gene expression and mRNA splicing data
Background: As genomes evolve after speciation, gene content, coding sequence, gene expression, and splicing all diverge with time from ancestors with close relatives. A minimum e...
Roald Rossnes, Ingvar Eidhammer, David A. Liberles
ICDT
2003
ACM
150views Database» more  ICDT 2003»
14 years 23 days ago
Bioinformatics Adventures in Database Research
Informatics has helped launch molecular biology into the genomic era. It appears certain that informatics will remain a major contributor to molecular biology in the post-genome er...
Jinyan Li, See-Kiong Ng, Limsoon Wong
BMCBI
2008
128views more  BMCBI 2008»
13 years 7 months ago
Validation of an NSP-based (negative selection pattern) gene family identification strategy
Background: Gene family identification from ESTs can be a valuable resource for analysis of genome evolution but presents unique challenges in organisms for which the entire genom...
Ronald L. Frank, Cyriac Kandoth, Fikret Erç...