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BMCBI
2004
158views more  BMCBI 2004»
13 years 7 months ago
Improvement of alignment accuracy utilizing sequentially conserved motifs
Background: Multiple sequence alignment algorithms are very important tools in molecular biology today. Accurate alignment of proteins is central to several areas such as homology...
Saikat Chakrabarti, Nitin Bhardwaj, Prem A. Anand,...
BMCBI
2011
13 years 2 months ago
Detection of viral sequence fragments of HIV-1 subfamilies yet unknown
Background: Methods of determining whether or not any particular HIV-1 sequence stems - completely or in part - from some unknown HIV-1 subtype are important for the design of vac...
Thomas Unterthiner, Anne-Kathrin Schultz, Jan Bull...
BMCBI
2010
182views more  BMCBI 2010»
13 years 7 months ago
L2-norm multiple kernel learning and its application to biomedical data fusion
Background: This paper introduces the notion of optimizing different norms in the dual problem of support vector machines with multiple kernels. The selection of norms yields diff...
Shi Yu, Tillmann Falck, Anneleen Daemen, Lé...
BMCBI
2007
106views more  BMCBI 2007»
13 years 7 months ago
Constructing a meaningful evolutionary average at the phylogenetic center of mass
Background: As a consequence of the evolutionary process, data collected from related species tend to be similar. This similarity by descent can obscure subtler signals in the dat...
Eric A. Stone, Arend Sidow
CSB
2004
IEEE
126views Bioinformatics» more  CSB 2004»
13 years 11 months ago
Boosted PRIM with Application to Searching for Oncogenic Pathway of Lung Cancer
Boosted PRIM (Patient Rule Induction Method) is a new algorithm developed for two-class classification problems. PRIM is a variation of those Tree-Based methods ( [4] Ch9.3), seek...
Pei Wang, Young Kim, Jonathan R. Pollack, Robert T...