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BMCBI
2007
179views more  BMCBI 2007»
13 years 10 months ago
rMotifGen: random motif generator for DNA and protein sequences
Background: Detection of short, subtle conserved motif regions within a set of related DNA or amino acid sequences can lead to discoveries about important regulatory domains such ...
Eric C. Rouchka, C. Timothy Hardin
BMCBI
2007
115views more  BMCBI 2007»
13 years 10 months ago
Comparing sequences without using alignments: application to HIV/SIV subtyping
Background: In general, the construction of trees is based on sequence alignments. This procedure, however, leads to loss of informationwhen parts of sequence alignments (for inst...
Gilles Didier, Laurent Debomy, Maude Pupin, Ming Z...
BMCBI
2010
151views more  BMCBI 2010»
13 years 10 months ago
Misty Mountain clustering: application to fast unsupervised flow cytometry gating
Background: There are many important clustering questions in computational biology for which no satisfactory method exists. Automated clustering algorithms, when applied to large,...
István P. Sugár, Stuart C. Sealfon
BMCBI
2008
81views more  BMCBI 2008»
13 years 10 months ago
A perspective for biomedical data integration: Design of databases for flow cytometry
Background: The integration of biomedical information is essential for tackling medical problems. We describe a data model in the domain of flow cytometry (FC) allowing for massiv...
John Drakos, Marina Karakantza, Nicholas C. Zoumbo...
BMCBI
2008
175views more  BMCBI 2008»
13 years 10 months ago
Synonym set extraction from the biomedical literature by lexical pattern discovery
Background: Although there are a large number of thesauri for the biomedical domain many of them lack coverage in terms and their variant forms. Automatic thesaurus construction b...
John McCrae, Nigel Collier
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