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BMCBI
2010
172views more  BMCBI 2010»
13 years 9 months ago
Comparison of evolutionary algorithms in gene regulatory network model inference
Background: The evolution of high throughput technologies that measure gene expression levels has created a data base for inferring GRNs (a process also known as reverse engineeri...
Alina Sîrbu, Heather J. Ruskin, Martin Crane
BMCBI
2010
175views more  BMCBI 2010»
13 years 9 months ago
Towards high performance computing for molecular structure prediction using IBM Cell Broadband Engine - an implementation perspe
Background: RNA structure prediction problem is a computationally complex task, especially with pseudo-knots. The problem is well-studied in existing literature and predominantly ...
S. P. T. Krishnan, Sim Sze Liang, Bharadwaj Veerav...
BMCBI
2010
205views more  BMCBI 2010»
13 years 9 months ago
A fast indexing approach for protein structure comparison
Background: Protein structure comparison is a fundamental task in structural biology. While the number of known protein structures has grown rapidly over the last decade, searchin...
Lei Zhang, James Bailey, Arun Siddharth Konagurthu...
BMCBI
2007
148views more  BMCBI 2007»
13 years 9 months ago
Evaluation of gene-expression clustering via mutual information distance measure
Background: The definition of a distance measure plays a key role in the evaluation of different clustering solutions of gene expression profiles. In this empirical study we compa...
Ido Priness, Oded Maimon, Irad E. Ben-Gal
BMCBI
2010
122views more  BMCBI 2010»
13 years 9 months ago
Simultaneous prediction of transcription factor binding sites in a group of prokaryotic genomes
Background: Our current understanding of transcription factor binding sites (TFBSs) in sequenced prokaryotic genomes is very limited due to the lack of an accurate and efficient c...
Shaoqiang Zhang, Shan Li, Phuc T. Pham, Zhengchang...